Publish in this journal
Journal Information
Vol. 206. Issue 7.
Pages 340-342 (July 2006)
Share
Share
Download PDF
More article options
ePub
Vol. 206. Issue 7.
Pages 340-342 (July 2006)
DOI: 10.1157/13090483
Quimerismo: origen e implicaciones médicas
Chimerism: origin and medical implications
Visits
28901
B. Fleta Asína, M C. Gonzalvo Liartea, P Cía Gómeza
a Servicio de Medicina Interna. Hospital Cl??nico Universitario Lozano Blesa. Zaragoza.
This item has received
28901
Visits
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Se denomina «quimera» al organismo formado por células procedentes de distintos individuos. Se trata de un fenómeno frecuente en la naturaleza que puede aparecer tras la gestación, un trasplante de órganos o una transfusión. Se ha relacionado con el desarrollo de enfermedades autoinmunes (EAI), concretamente la esclerodermia. La hipótesis que relaciona el quimerismo con las EAI surge de distintas observaciones, como la similitud de la esclerodermia con la enfermedad injerto contra huésped, la persistencia de células quiméricas en el tiempo y el hallazgo de mayor número de células quiméricas en mujeres afectas que en sanas. Este fenómeno no se asocia necesariamente a enfermedad, y podría ser de utilidad en diagnóstico prenatal e incluso estar implicado en la regeneración de órganos dañados.
The organism whose cells come from different individuals is called chimera. It is frequently observed in nature: pregnancy, organ transplantation or transfusion are considered chimeric cell sources. It has been involved in autoimmune diseases development such as scleroderma, because of similarities between it and graft versus host disease, long term persistence of fetal cells in women and the finding of greater number of chimeric cells in affected women than healthy ones. It is not strictly a disease but might be considered helpful in non-invasive prenatal diagnosis and damaged organs regeneration.

Article

These are the options to access the full texts of the publication Revista Clínica Española (English Edition)
Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Revista Clínica Española (English Edition)

Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
Email
Idiomas
Revista Clínica Española (English Edition)

Subscribe to our newsletter

Article options
Tools
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

es en
Política de cookies Cookies policy
Utilizamos cookies propias y de terceros para mejorar nuestros servicios y mostrarle publicidad relacionada con sus preferencias mediante el análisis de sus hábitos de navegación. Si continua navegando, consideramos que acepta su uso. Puede cambiar la configuración u obtener más información aquí. To improve our services and products, we use "cookies" (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here.