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DOI: 10.1016/j.rceng.2020.12.009
Available online 19 June 2021
Clinical characteristics of premature cardiovascular disease in our health area
Características clínicas de enfermedad vascular prematura en un área de salud
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M. Viscasillasa, I. Lamíquiz-Moneob, M.R. Pérez-Ruizb, R. Garcia-Fenollc, E. Jarautaa,c,
Corresponding author
estijarauta@gmail.com

Corresponding author.
a Facultad de Medicina, Universidad de Zaragoza, Zaragoza, Spain
b Unidad Clínica y de Investigación en Lípidos y Arteriosclerosis, Hospital Universitario Miguel Servet, Instituto de Investigación Sanitaria Aragón (IIS Aragón), CIBERCV, Zaragoza, Spain
c Servicio de Medicina Interna, Hospital Universitario Miguel Servet, Zaragoza, Spain
Received 08 June 2020. Accepted 29 December 2020
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Table 1. Characteristics of the population at the time of hospital admission according to type of CVD.
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Abstract
Introduction and objectives

Cardiovascular disease continues to be the main cause of mortality, but few data are available in the young population. The aim of our study was to know the incidence and clinical characteristics of premature cardiovascular disease in our health area.

Methods

Cross-sectional study of patients admitted for acute episode of premature cardiovascular disease in a referral hospital during 2018.

Results

We detected 367 subjects: 306 (83.4%) with atherosclerotic cardiovascular disease. Almost half (164, 44.7%) were diabetic, with primary hypercholesterolaemia or high cardiovascular risk, and 84 (22.9%) had a personal history of cardiovascular disease. Among those with elevated risk or history (n = 207) only 47 subjects had LDL cholesterol at therapeutic target.

Conclusions

Most of the subjects with premature cardiovascular disease in our study had higher cardiovascular risk than attributable to their age. Intensive diagnosis and treatment of cardiovascular risk factors may prevent cardiovascular disease in young adults.

Keywords:
Premature cardiovascular disease
Diabetes mellitus
Primary hypercholesterolaemia
Ischaemic heart disease
Cerebrovascular disease
Peripheral arterial disease
High-intensity statin treatment
Resumen
Introducción y objetivos

La enfermedad cardiovascular sigue siendo la principal causa de mortalidad, pero se disponen de pocos datos en población joven. El objetivo de nuestro estudio fue conocer la incidencia y características clínicas de la enfermedad cardiovascular prematura en nuestra área de salud.

Métodos

Estudio trasversal de pacientes ingresados por episodio agudo de enfermedad cardiovascular prematura en un hospital de referencia durante 2018.

Resultados

Se detectó a 367 sujetos: 306 (83,4%) con enfermedad cardiovascular aterosclerótica. Casi la mitad (164, 44,7%) eran diabéticos, con hipercolesterolemia primaria o alto riesgo cardiovascular, y 84 (22,9%) tenían antecedentes personales de enfermedad cardiovascular. De entre aquellos con riesgo elevado o antecedentes (n = 207), solo 47 sujetos tenían colesterol LDL en objetivo terapéutico.

Conclusiones

La mayoría de sujetos con enfermedad cardiovascular prematura de nuestro estudio presentaron mayor riesgo cardiovascular del atribuible a su edad. El diagnóstico y tratamiento intensivo de los factores de riesgo cardiovasculares pueden prevenir la enfermedad cardiovascular en adultos jóvenes.

Palabras clave:
Enfermedad cardiovascular prematura
Diabetes mellitus
Hipercolesterolemia primaria
Cardiopatía isquémica
Enfermedad cerebrovascular
Enfermedad arterial periférica
Estatinas de alta potencia

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