TY - JOUR T1 - Tp-e interval and Tp-e/QT ratio in patients with celiac disease JO - Revista Clínica Española T2 - AU - Demirtaş,K. AU - Yayla,Ç. AU - Yüksel,M. AU - Açar,B. AU - Ünal,S. AU - Ertem,A.G. AU - Kaplan,M. AU - Akpinar,M.Y. AU - Kiliç,Z.M.Y. AU - Kayaçetin,E. SN - 00142565 M3 - 10.1016/j.rce.2017.09.001 DO - 10.1016/j.rce.2017.09.001 UR - https://www.revclinesp.es/es-tp-e-interval-tp-e-qt-ratio-in-articulo-S0014256517302011 AB - ObjectivesCeliac disease is a chronic immune-mediated disease of the small intestine. It has been known that dilated cardiomyopathy and ischemic coronary artery disease have become more frequent in patients with celiac disease. The aim of the study was to assess Tp-e interval and Tp-e/QT ratio in patients with celiac disease. Material and methodsThis study was conducted at a single center in collaboration with gastroenterology and cardiology clinics. Between January 2014 and June 2015, a total of 76 consecutive patients were enrolled (38 patients with celiac disease and 38 control subjects). Tp-e interval, Tp-e/QT and Tp-e/QTc ratio were measured from the 12-lead electrocardiogram. ResultsTp-e interval (64.2±11.0 vs. 44.5±6.0; p<0.001), Tp-e/QT ratio (0.18±0.02 vs. 0.13±0.02; p<0.001) and Tp-e/QTc ratio (0.16±0.02 vs. 0.11±0.01; p<0.001) were significantly higher in patients with celiac disease than control subjects. There was a significant positive correlation between Tp-e/QTc ratio and disease duration in patients with celiac disease (r=0.480, p=0.003) and also there was a significant positive correlation between Tp-e/QTc ratio and erythrocyte sedimentation rate (r=0.434, p<0.001). ConclusionsOur study showed that Tp-e interval, Tp-e/QT and Tp-e/QTc ratios were increased in patients with celiac disease. Whether these changes increase the risk of ventricular arrhythmia deserve further studies. ER -